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Selfology Ingredient FAQ -

What is

Phenethyl Alcohol

& it's various names,

 

Phenethyl alcohol,

Benzeneethanol ,

2-Phenylethanol ,

2-Phenylethyl alcohol,

β-Phenylethanol,

β-Phenylethyl alcohol,Benzyl-carbinol,

β-Hydroxyethylbenzene。
 

Chinese Names:

β-苯乙醇,

β-苯乙醇,

苯乙醇,

苄基甲醇,

β-苯基乙醇,

2- 苯基乙醇

 

 

A Great Introduction from a Research Paper,

 

2-苯乙醇最早是作為玫瑰花中特徵性的香氣化合物被發現的[2]。在大馬士革玫瑰的香精油中,2- 苯乙醇占到其總揮 發物含 量的60%以上[3]。 2-苯乙醇由於具有玫瑰花的芳香而備受人們歡迎和喜愛,使 2-苯乙醇成為在香水和化妝品行業中應用最廣泛的香料化合物[4]。此外,2- 苯乙 醇還作為香精廣泛應用在食品行業中,如飲料、麵包、餅乾、口香糖等。

 

據估計在 1990 年全球市場對 2-苯乙醇的銷售量大約為 7000 t·a−1[5]。目前市場上的 2-苯乙醇主要是靠化學合成方法生產的,但由於2-苯乙醇的應用領域而使人們更傾向於使用“天然”來源的 2-苯乙醇;而且

利用標記為“天然”的原材料來合成的 2-苯乙醇價格要遠高於化學法合成的2- 苯乙醇。其差別在於生產方法不同,在歐美國家標記為“天然”的香料在生產時必須利用天然原材料通過物理方法,酶催化方法及微生物轉化法來生產[6]。在 2002 年全球“天然”2-苯乙醇的全球市場銷售只有0.5 t,其價格在US $1000 kg−1左右[1,7]。這篇綜述將從2-苯乙醇的生產方法、生物合成、生理學作用以及應用等方面對 2-苯乙醇進行詳細

的總結

 

 SOURCE: 

 https://image.hanspub.org/Html/698.html

 

 

 

 

 

JOURNAL OF THE AMERICAN COLLEGE OF TOXICOLOGY

Volume 9, Number 2,1990

Mary Ann Liebert, Inc., Publishers

4

Final Report on the Safety Assessment of

Phenethyl Alcohol

 

  • Maternal exposure to PEA, microencapsulated in the feed, at concentrations of 1000, 3000, and 10,000 ppm had no effect on embryo-fetal loss, or embryo-fetal development and morphology.

  • There was an increased incidence of incomplete ossification in the 10,000 ppm PEA group litters.

  • Doses of 0.14, 0.43, and 1.40 ml/kg of PEA were applied to the skin of pregnant rats.

  • Maternal toxicity was marked at the highest dose, Morphological abnormalities in fetuses in the 1.40 ml/kg PEA group were observed.

  • The number of fetuses with moderate degrees of reduced ossification and with cervical rib(s) was significantly greater in the 0.43 ml/kg PEA group than in the controls.

  • The incidence of structural changes was slightly greater in 0.14 ml/kg PEA-treated rats than in control rats. Dermal doses of 0.07,0.14,0.28,0.43, and 0.70 ml/kg/day PEA to pregnant rats significantly increased cervical ribs in the 0.70 ml/kg/day group litters.

  • The highest no observed adverse effect level (NOAEL) was 0.43 ml/kg/day for cervical rib malformation (teratogenic effect).

  • The dermal applied teratogenicity NOAEL of 0.43 ml/kg/day was used to estimate a safe use level of 1.0% PEA in cosmetic products.'')   

 

 

 

DEFINITIONS 

cervical rib is an abnormality that's present from birth. It doesn't usually cause problems, but if it presses on nearby nerves and blood vessels, it can cause neck pain, numbness in the arm and other symptoms, which collectively are known as thoracic outlet syndrome.

 

Ossification (or osteogenesis) in bone remodeling is the process of laying down new bone material by cells called osteoblasts. It is synonymous with bone tissue formation.

KEYS COLLECTION

Phenethyl Alcohol,

"nervous system", the "brain" and the "reproductive system".

Alcohols are drying to the skin

Antimicrobial Preservative

Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications

Cervical Rib 

Ossification 

No Observed Adverse Effect Level (NOAEL)

苯乙醇

1% Max

 

 

Journals and Articles regarding the Safety of this Chemical,

 

 

  

 

 

 

Source: http://chemicaloftheday.squarespace.com/todays-chemical/2011/2/28/phenoxyethanol.html

 

 

The impact of ethylene glycol monomethyl ether on ovarian function may extend to the next generation in female mice: a preliminary study.

 

Abstract

 

Ethylene glycol monomethyl ether (EGME) is known to alter the reproductive function of exposed animals and their offspring; however, its influence on cumulus-oocyte complexes (COCs) remains unclear. This study assessed the toxicity of EGME on oocytes and COCs by analyzing the number of oocytes in the F0 and F1 generations and evaluating apoptosis in oocytes and COCs after treating the F0 generation with EGME. There was a dose-dependent increase in the apoptosis ratios in the COCs from F1 mice, which were not directly exposed to EGME, with apoptosis ratios of 0.065, 0.102, 0.184, and 0.212 for the 0%, 0.05%, 0.1%, and 0.2% EGME dose groups, respectively. The increased apoptosis of cumulus cells may play a role in the toxicity of EGME toward ovarian function. EGME toxicity seems to affect female offspring in future generation(s), but further studies with a large number of animals are necessary to verify these conclusions.

*Selfology FAQ  on Ingredient - "Hair Dye Chemical Series" exploring deep question such as hair dye effects on our scalp and ageing.

 

 

Conventional hair dye is made with harmful chemicals that are put directly on the scalp each time hair is dyed, either at home or in the salon. Salon workers are even more exposed to these chemicals – potentially to carcinogenic levels of harm – as they may perform multiple hair dying sessions in a day.

 

When you purchase hair dye at the store, the ingredients are required to be listed on the label. Whether you can make sense of those labels may be another story altogether, as ingredients listed can be complex and hard to decode. However, salon products do not even have to list ingredients, because of loose language in . The FDA does not require “For Professional Use Only” products, which include some dyes sold directly to stylists, to list the ingredients on packaging. This means your stylist might not even know themselves what ingredients are in your salon hair color.

 

First we have confirmation  that it is bad for you and as long as you keep it away from your scalp, and then we begin to wonder why would anyone put these chemcals near any where on their skin, our largest organ, and how does it affect the lymphatic systems, from the head's scalp to the rest of your body including the nervous systems, how these they do have heavy metalic dyes - especially the ones from many retails outlets)

 

Selfology Heart Office

To be continued....stay tuned or sign up for email updates here, 

.

Google Translation: 

 

2-Phenylethanol was first discovered as a characteristic aroma compound in roses [2]. Among the essential oils of the rose of Damascus, 2-phenylethanol accounts for more than 60% of its total volatile content [3]. 2-Phenylethanol is popular and loved because of its rose aroma, making 2-phenylethanol the most widely used perfume compound in the perfume and cosmetics industry [4]. In addition, 2-phenethyl alcohol is also widely used as a flavor in the food industry, such as beverages, bread, biscuits, chewing gum, etc. It is estimated that the global market for 2-phenylethanol sales in 1990 was approximately 7000 t · a−1 [5]. At present, 2-phenylethanol is mainly produced by chemical synthesis methods, but because of the application fields of 2-phenylethanol, people tend to use 2-phenylethanol from "natural" sources; andThe price of 2-phenylethanol synthesized from raw materials marked as "natural" is much higher than that of 2-phenylethanol synthesized chemically. The difference lies in the different production methods. In the European and American countries, the spices labeled "natural" must be produced using physical raw materials through physical methods, enzyme-catalyzed methods, and microbial transformation methods [6]. In 2002, the global "natural" 2-phenylethanol market was sold at only 0.5 t, and its price was around US $ 1000 kg−1 [1,7]. This review will detail 2-phenylethanol from its production methods, biosynthesis, physiological effects, and applications.Summary  SOURCE: https://image.hanspub.org/Html/698.html

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